Ozone Therapy on Cerebral Blood Flow: A Preliminary Report
Ozone Therapy on Cerebral Blood Flow: A Preliminary Report Bernardino Clavo1,2,7, Luis Catalá3,7, Juan L. Pérez2,4,7, Victor Rodríguez5 and Francisco Robaina2,6,7 Departments of 1Radiation Oncology and 2Research Unit, 3Radiology, 4Medical Physics and 6Chronic Pain Unit, Dr Negrín Hospital, 5La Paterna Medical Center and 7Canary Islands Institute for Cancer Research (ICIC), Las Palmas (Canary Islands), Spain Ozone therapy is currently being used in the treatment of ischemic disorders, but the underlying mechanisms that result in successful treatment are not well known. This study assesses the effect of ozone therapy on the blood flow in the middle cerebral and common carotid arteries. Seven subjects were recruited for the therapy that was performed by transfusing ozone-enriched autologous blood on 3 alternate days over 1 week. Blood flow quantification in the common carotid artery (n 14) was performed using color Doppler. Systolic and diastolic velocities in the middle cerebral artery...