Could a chicory compound reduce Alzheimer's-related memory loss? Memory loss is a key characteristic of Alzheimer's disease, which is a condition that affects more than 5.4 million people in the United States. In a new study, researchers report that a compound called chicoric acid, naturally present in chicory, may be effective in reducing Alzheimer's-related memory loss. Researchers suggest that a compound found in chicory has the potential to reduce memory loss associated with Alzheimer's disease. The study, recently published in The FASEB Journal , reveals that mice treated with chicoric acid displayed better memory in behavioral tests than rodents that did not receive the compound. While further research is needed, study co-author Xuebo Liu, Ph.D., of the College of Food Science and Engineering at Northwest A&F University in China, and colleagues say that it is possible for chicoric acid to help maintain memory in patients with Alzheimer's and other ne...
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Ocak, 2017 tarihine ait yayınlar gösteriliyor
Renoprotective Effects of Megadose Vitamin C on cisplatin-induced kidney injury
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Renoprotective effects of megadose vitamin C on cisplatin-induced kidney injury Supa Sithanukul 1 Chollada Buranakarl 1* Chutamas Benjanirut 1 Anudep Rungsipipat 2 ABSTRACT Cisplatin (CDDP)-induced nephrotoxicity is mediated via oxidative stress and may be alleviated using antioxidant activity. Although megadose of vitamin C may cause oxalate nephropathy and apoptosis, the antioxidant effect of vitamin C may be beneficial when given along with CDDP. The objective of this study was to investigate the renoprotective effects of megadose vitamin C on rats receiving CDDP. Rats were divided into 4 groups: group 1, control rats (CONT); group 2, vitamin C-treated rats (VIT C); group 3, CDDP-treated rats (CDDP) and group 4, CDDP + vitamin C-treated rats (CDDP + VIT C). Vitamin C (1000 mg/kg) was given intravenously to the VIT C and CDDP + VIT C groups while CDDP (6 mg/kg) was injected intraperitoneally into the CDDP and CDDP + VIT C groups. Renal func...